Dr. Antonio Privitera

Lateral Internal Sphincterotomy (LIS) Explained

Medical diagram showing lateral internal sphincterotomy with open and closed techniques highlighting sphincter division at the lateral position
LIS reduces sphincter pressure by making a precise cut at the side of the anal canal, allowing the fissure to heal.

Lateral internal sphincterotomy (LIS) is the most effective surgical treatment for chronic anal fissure. For a complete overview of all treatment options, see anal fissure treatment in Dubai.

I perform LIS regularly in Dubai and Abu Dhabi. This guide explains exactly what the procedure involves, what to expect, and how to decide if it is the right treatment for your situation.

  • Indication: chronic fissure not responding to medical treatment
  • Goal: reduce sphincter pressure and allow healing
  • Outcome: high healing rate with low recurrence

What Is Lateral Internal Sphincterotomy?

LIS involves dividing part of the internal anal sphincter the involuntary muscle whose spasm causes chronic fissures and prevents healing. By making a precise cut in this muscle, we permanently reduce resting anal pressure, restore blood supply to the posterior midline, and allow the fissure to heal.

The word ‘lateral’ is important: the cut is made at the 3 or 9 o’clock position (the side), NOT at the site of the fissure (the back). This is deliberate cutting at the fissure site (‘posterior sphincterotomy’) carries higher incontinence risk and has been largely abandoned. Understanding chronic fissures is essential. See why chronic fissures don’t heal.

Diagram showing how lateral internal sphincterotomy reduces pressure, improves blood flow, and allows anal fissure healing
By lowering sphincter pressure, LIS restores blood supply and creates the conditions needed for fissure healing.

The Procedure: Step by Step

Before Surgery

  • Day-case procedure you arrive in the morning and go home the same day
  • General anesthesia (most common), spinal anesthesia, or local anesthesia with sedation
  • No bowel preparation required
  • Fast for 4-6 hours before surgery (solids)

During Surgery

  • You are positioned in lithotomy (on your back, legs raised) or prone (face down)
  • The procedure takes 15-30 minutes
  • Two techniques: Open (a small skin incision is made and the sphincter is divided under direct vision) or Closed/subcutaneous (a fine blade is passed into the intersphincteric groove and the sphincter divided without a skin incision most common in UAE)
  • The sentinel pile (if present) and any hypertrophied papilla may be excised at the same time

After Surgery

  • Recover in the day-surgery unit for 1-3 hours
  • Go home when pain is controlled and you have passed urine
  • Some patients experience temporary difficulty with urination immediately after surgery this is normal and resolves

Recovery

  • Pain: Significant improvement is usually noticed within 1-2 weeks as the spasm is relieved. The wound itself may be tender for 2-4 weeks.
  • Work: Desk work: 3-7 days.
  • Manual labor: 2-4 weeks.
  • Driving: 3-7 days (until you are off narcotic pain relief and comfortable)
  • Exercise: Light walking from day 1.
  • Gym and heavy lifting: 4 weeks.
  • Full healing: 4-8 weeks
Infographic showing recovery timeline after lateral internal sphincterotomy including pain relief and healing over 4 to 8 weeks
Most patients experience rapid pain relief, with complete healing typically within 4–8 weeks.

Results

  • Healing rate: >95% for appropriately selected chronic fissures
  • Pain relief: Most patients experience significant or complete relief within 2 weeks of surgery
  • Recurrence: Very low <5% in most series

Risks and Side Effects

Incontinence – The Most Important Risk

The most significant risk of LIS is minor fecal incontinence difficulty controlling gas or liquid stool. The reported rate varies widely (1-30% depending on how it is measured and how long patients are followed), but significant, persistent incontinence with solid stool is rare in experienced hands.

Risk factors for incontinence after LIS: prior anorectal surgery, sphincter injury from childbirth, low preoperative sphincter pressure. These are assessed before deciding to proceed with surgery.

Other Risks

  • Infection: Uncommon the perianal area has good blood supply
  • Bleeding: Minor, usually self-limiting
  • Fissure recurrence: <5%
  • Incomplete healing: Rare usually indicates Crohn’s disease or other underlying condition

LIS vs Botox: Which Is Right for You?

I discuss this with every patient individually. In general:

  • LIS is preferred when: Creams and Botox have failed; the patient has very high resting sphincter pressure; the fissure has been chronic for years; the patient wants a definitive, one-time treatment and understands the incontinence risk.
  • Botox is preferred when: The patient wants to avoid surgery; the fissure is moderately chronic; the patient is concerned about incontinence risk; first-line treatment failure.

This is usually considered after conservative treatment fails. Learn more about Botox treatment for fissure.

References

  • American Society of Colon and Rectal Surgeons. Practice parameters for the management of anal fissures. Dis Colon Rectum. 2017.
  • Altomare DF et al. Lateral internal sphincterotomy for chronic anal fissure. Br J Surg. 2019.

AUTHOR AUTHORITY BLOCK
All content on this page is written and reviewed by Prof. Dr. Antonio Privitera, consultant colorectal surgeon, with fellowship training at the Mayo Clinic (USA) and the Royal College of Surgeons (UK), and European Board Certification in Colorectal Surgery. Dr. Privitera practises across Dubai and Abu Dhabi and specialises in the full range of anorectal conditions including hemorrhoids, anal fissure, anal fistula, and colorectal cancer.

About the Author

Professor Dr Antonio Privitera
Consultant Colorectal & General Surgeon | Proctologist
FRCS (England)
FASCRS
MD
PhD
70+ Publications
Mayo Clinic Fellowship

Dr. Privitera is the only surgeon in the world with both a Mayo Clinic (Rochester, USA) and University of London Colorectal Surgery Fellowship. He completed an advanced laparoscopic and robotic fellowship in Seoul, South Korea.

He previously served as Lead Colorectal Surgeon at Tawam Hospital–Johns Hopkins Abu Dhabi and Associate Professor at UAE University.

He is a Fellow of the American Society of Colon and Rectal Surgery (FASCRS), Fellow of the Royal College of Surgeons of England (FRCS), and author of over 70 peer-reviewed publications. He also served as General Secretary of the Emirates Society of Colon and Rectal Surgery (2021–2024).

He practices across Dubai and Abu Dhabi.

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